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IONIS PHARMACEUTICALS INCIONS

Latest proxy: 2026 · view on SEC ↗ · CIK 0000874015

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CEO total pay

$13,350,777

Brett P. Monia · 2025

Say on pay

96%

Latest disclosed shareholder vote

CEO pay ratio

CD&A

44 to 1

Median employee: $304,680

Compensation committee

CD&A

Compensation Committee

Per the latest proxy

Filings indexed: 2 · 2026 · 2025

Executive pay

What did they pay them?

From the Summary Compensation Table. Pay mix and YoY are computed from these rows.

Executive	Role	TotalYoY	Pay mix	Salary	Stock	Cash incentive	Other
Brett P. Monia2025 compensation	Chief Executive Officer	$13,350,777↓ 13%	88% at-risk	$1,051,776	$4,297,208	—	$18,009
Elizabeth L. Hougen2025 compensation	EVP, Finance and Chief Financial Officer	$4,422,302↓ 13%	79% at-risk	$729,750	$1,544,265	—	$43,009
Richard S. Geary2025 compensation	EVP, Chief Development Officer	$3,331,400↓ 4%	76% at-risk	$622,074	$1,095,930	—	$47,831
Brian Birchler2025 compensation	EVP, Corporate and Development Operations	$3,245,054	77% at-risk	$580,154	$1,095,930	—	$48,009
Eric Swayze2025 compensation	EVP, Research	$3,233,339	77% at-risk	$589,013	$1,095,930	—	$18,009
Patrick R. O’Neil2025 compensation	EVP, Chief Legal Officer and General Counsel	$3,210,608↓ 6%	76% at-risk	$611,791	$1,095,930	—	$18,009

Pay mix: base cash incentive equity other

Add to peer comparison →Year-over-year diff →

CD&A excerpt

Compensation discussion & analysis

Opening passage of the loaded filing's CD&A. Use Ask below to query the full text with citations.

2025 NEOs, 2025 “Say on Pay” Vote and Summary of Recent Compensation and Governance Changes Named Executive Officers. On December 31, 2025, our Chief Executive Officer, Chief Financial Officer, and our four9 other most highly compensated executive officers, called our “named executive officers” or “NEOs,” were as follows: Name Title Brett P. Monia Chief Executive Officer Elizabeth L. Hougen Executive Vice President, Chief Financial Officer Richard S. Geary Executive Vice President, Chief Development Officer Brian Birchler Executive Vice President, Corporate and Development Operations Eric Swayze Executive Vice President, Research Patrick R. O’Neil Executive Vice President, Chief Legal Officer and General Counsel “Say on Pay” Vote. In June 2025, we held a stockholder advisory vote on the compensation of our named executive officers. Our stockholders overwhelmingly approved, on an advisory (nonbinding) basis, the compensation of our named executive officers, with approximately 96% of stockholder votes cast in favor of our “say on pay” resolution. In evaluating our general compensation practices during 2025 and in early 2026, we were mindful of the strong support our stockholders expr…

Read the full CD&A on SEC.gov ↗

Peer comparison

Who they benchmark against

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Governance

Policy guardrails

hedging
prohibited
“Anti-Hedging Policy and Anti-Pledging Policy We explicitly prohibit employees from “shorting” and hedging against our stock and from pledging our stock”
pledging
prohibited
“In addition, we also prohibit all directors and employees, including our named executive officers, from pledging our stock as collateral”
clawback
present
“Clawback Policy We have a recoupment/“clawback” policy”
stock ownership guidelines
present
“Stock Ownership Guidelines and Holding Periods”
change in control
Severance and Change in Control Arrangements
“Severance and Change in Control Arrangements”
compensation consultant
independent
“independent compensation consultant”
compensation committee
Compensation Committee
“The Compensation Committee”

Performance markers

Metric facts

revenue
$2.7 billion
“evaluation of each key objective and the related achievements for 2025. The Compensation Committee set the Company Performance Factor for the 2025 MBO award at 190% in recognition of a year full of many significant accom…”
time equity mix
—
“inued or substituted and that are held by Participants whose Continuous Service has not terminated prior to the effective time of the Corporate Transaction (referred to as the “Current Participants”), the vesting of any …”
say on pay
96%
“votes cast in favor of our “say on pay””
ceo pay ratio
44 to 1
“of the Summary Compensation Table. For 2025, the median annual total compensation of our employees (other than our CEO) was $304,680 and the annual total compensation of our CEO, as reported in the Summary Compensation T…”
median employee compensation
$304,680
“our median employee for 2024 using the following methodology: •We included all employees of Ionis who were employed by us on December 31, 2024. 86 •We identified our median employee from this employee population based on…”

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